This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: o Sea sponge metabolite o Binds and stabilizes F-actin competitively with phalloidin o Causes nucleation o Cell permeant o Nanomolar Kd for F-actin Latrunculin o Sea sponge metabolite o Binds monomeric actin o inhibits polymerization o Cell permeant o Active at low nanomolar MF Binding Molecules...
View Full Document
- Fall '10