a copy of the transposon still remains in the original location and the overall copy number of the t

A copy of the transposon still remains in the original location and the overall copy number of the t

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
----- a copy of the transposon still remains in the original location and the overall copy number of the transposon increases in the cell. Replicative Transposition may involve the formation of a DNA intermediate or an RNA intermediate. When transposition occurs between two circular DNA molecules an intermediate known as a cointegrate is believed to be formed. In this process, the transposon is replicated and briefly a large cointegrate (which is composed of both circular DNAs and both transposons) is formed by the
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: transposase enzyme. The cointegrate is then resolved by an enzyme known as resolvase into two circular DNAs each containing a copy of the transposon. Transposition involving RNA intermediates closely resembles the process by which retroviruses copy their RNA genome into a double-stranded DNA molecule using the enzyme reverse transcriptase. Most transposons found in eukaryotic cells transpose via RNA intermediates including those found in humans....
View Full Document

This document was uploaded on 11/03/2011 for the course BIOLOGY MCB2010 at Broward College.

Ask a homework question - tutors are online