Attaching Amino Acids to tRNAs

Attaching Amino Acids to tRNAs - must be able to...

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Attaching Amino Acids to tRNAs The amino acid attachment site is located at the 3'OH terminus The amino acid, corresponding to the specific tRNA anticodon, is covalently linked to this terminus. Amino acids will come off to form polypeptide chain during protein synthesis. tRNAs are actually Amino acid carriers With the help of a specific enzyme the tRNA recognizes and binds to a specific amino acid. The enzymes are termed: aminoacyl tRNA synthetases ( Fig. 4 ). There is a different synthetase enzyme for every amino acid. A specific aminoacyl tRNA synthetase matches the amino acid with the anticodon; to do so, the enzyme
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Unformatted text preview: must be able to distinguish one tRNA molecule from another. The necessary distinction is provided by an as yet ill-defined region encompassing many parts of the tRNA molecule called the recognition site. At the opposite end of the molecule is a loop which contains the anticodon. As the mRNA codons are read, only the appropriate tRNA can hydrogen bond with the codon by virtue of the anticodon. [See Figure 7.2 in text of how enzyme adds amino acid to the tRNA.] G A A mRNA codon | | | C U U tRNA anticodons...
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This document was uploaded on 11/03/2011 for the course BIOLOGY MCB2010 at Broward College.

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