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Unformatted text preview: anchor the cytoskeleton to areas of cell contact. The sites of attachment - focal adhesions- also serve as attachment sites for large bundles of actin filaments that are termed stress fibers. Stress fibers- are contractile bundles of actin filaments cross-linked by alpha-actinin. These bundles anchor the cell and exert tension against the subsratum. They are attached to the plasma membrane at focal adhesions via interactions with integrin. The actin cytoskeleton is similarly anchored to regions of cell-cell contact called adherins junctions. This attachment is mediated by a family of proteins known as adherins. ACTIN ALSO PLAYS A MAJOR ROLE IN MUSCLE CONTRACTION...
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This document was uploaded on 11/03/2011 for the course BIOLOGY MCB2010 at Broward College.
- Fall '10