Post - the primary transcript near this site, and poly(A)...

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Post-transcriptional Modification to form mRNA The primary eukaryotic transcript must be modified in several ways in order to form a mature mRNA. First, shortly after transcription begins, a CAP is added to the 5' end of the transcript. This CAP is a 7-methyl guanosine . Polyadenylation must also occur. In animal cells, the consensus sequence: A A U A A A is a signal sequence for polyadenylation. An endonuclease cleaves
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Unformatted text preview: the primary transcript near this site, and poly(A) polymerase adds the poly(A) tail to the 3' end of the cut. Two hundred or more As may be added! Finally, all introns [intervening sequences] are removed in a process known as RNA splicing and the remaining exons are joined to yield the mature mRNA....
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