Post - the primary transcript near this site and poly(A...

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Post-transcriptional Modification to form mRNA The primary eukaryotic transcript must be modified in several ways in order to form a mature mRNA. First, shortly after transcription begins, a CAP is added to the 5' end of the transcript. This CAP is a 7-methyl guanosine . Polyadenylation must also occur. In animal cells, the consensus sequence: A A U A A A is a signal sequence for polyadenylation. An endonuclease cleaves
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Unformatted text preview: the primary transcript near this site, and poly(A) polymerase adds the poly(A) tail to the 3' end of the cut. Two hundred or more As may be added! • Finally, all introns [intervening sequences] are removed in a process known as RNA splicing and the remaining exons are joined to yield the mature mRNA....
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This document was uploaded on 11/03/2011 for the course BIOLOGY MCB2010 at Broward College.

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