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RNA Structure - hydrogen The 2 hydroxyl is left free when...

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RNA Structure The nitrogenous base, Uracil , is used in place of thymine ( Fig. 1 ) but it acts just like thymine in pairing with adenine . When RNA is formed using the DNA template (coding strand) The A in the DNA is transcribed to a U in RNA The T in the DNA is transcribed to an A in RNA The G in the DNA is transcribed to a C in RNA The C in the DNA is transcribed to a G in RNA The use of Ribose in RNA instead of Deoxyribose ( Fig. 2 ). In the chemical structure of ribose, at the 2' C there is a hydroxyl group instead of a
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Unformatted text preview: hydrogen. The 2' hydroxyl is left free when ribonucleotides are linked to form RNA. This leaves RNA less chemically stable with a tendency for hydrolytic cleavage, especially in strong base ( Fig. 3 ). In contrast, the key to the genetic code is stability over a long period of time, therefore DNA has the advantage. For same reason of instability, RNA has been more difficult to study than DNA....
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