Termination of translation

Termination of translation - hydrolysis of the bond between...

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Termination of translation Begins when a stop codon appears after translocation in the A site of the ribosome ( UAA, UAG, UGA ). There is no tRNA that can base pair with the stop codons. Instead release factor RF-1 specifically binds to UAA or UAG in the A site and RF- 2 specifically binds to UGA . Both release factors if inserted cause the
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Unformatted text preview: hydrolysis of the bond between the tRNA in the P site and the polypeptide chain that is attached to it: The result is the release of the newly synthesized polypeptide. • This release in turn causes the complex to dissociate and mRNA, tRNA and ribosomal subunits are freed....
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This document was uploaded on 11/03/2011 for the course BIOLOGY MCB2010 at Broward College.

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