The route for - signal sequence in their amino terminus...

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The route for secreted proteins is: ER ---- Golgi ---- cell exterior The route for lysosomal proteins is: ER ---- Golgi ---- lysosome The route for Golgi proteins is: ER ---- Golgi How is the cell able to differ which protein should be translated from membrane- bound ribosomes and which from free ribosomes? Proteins are targeted to the ER by a
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Unformatted text preview: signal sequence in their amino terminus! Experimental evidence for signal sequence in secreted proteins : -- in vitro translation of mRNAs on free ribosomes yielded slightly larger proteins. -- If rough ER was added to test tube: cleavage to normal size and location in ER...
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This document was uploaded on 11/03/2011 for the course BIOLOGY MCB2010 at Broward College.

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