BMB401 F03 T4 KEY

BMB401 F03 T4 KEY - I(Name have neither received nor given help BMB 401/506 Fall 2003 5 The antibiotic puromycin A Inhibits translocation B

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I, (Name) _________________________________________ have neither received nor given help BMB 401/506 – Fall 2003 Fourth Examination December 4, 2003 KEY During this exam you should not be in possession of a beeper or a cellular phone. Please place your beeper or cellular phone in your book bag (after you turn it off!!) and place the bag against the wall of the room. You can only use calculators that do not have memory capabilities for alphabetic characters. Other calculators should also be placed in your bag. THESE ARE STANDARD SINGLE ANSWER MULTIPLE CHOICE QUESTIONS. THE POSSIBLE ANSWERS ARE LABELED A, B, C, D AND E. SELECT THE SINGLE BEST ANSWER AND MARK THE APPROPRIATE CIRCLE ON THE SCANTRON ANSWER SHEET. Bubble in your name and ID# (C# please). There are 32 questions. You will receive full credit for 30 correct answers. 1. Which protein has the unusual ability to bind DNA in the minor groove? A. RNA polymerase I B. TFIIB C. TATA box-binding protein TBP D. Sigma factor E. None of the above. 2. What are the differences between A and B DNA? A. The B DNA double helix is more elongated (in terms of rise per base pair) but narrower than the A helix. B. The A DNA double helix is more elongated but narrower than the B helix. C. The A helix has wider major grooves than the B helix. D. The A helix is left-handed, whereas the B helix is right-handed. E. A and C. 3. RNA polymerase II transcribes : A. tRNA genes B. tRNA and small rRNA genes C. rRNA genes D. protein-coding genes. E. A, B and C. 4. Which of the following proteins are NOT involved in DNA replication in prokaryotic cells: A. DNA polymerase I B. DNA polymerase III C. Topoisomerase II D. Primase E. All are involved, no exception 5. The antibiotic puromycin: A. Inhibits translocation B. Promotes chain termination C. Inhibits binding of charged tRNA to the ribosome D. Inhibits peptidyl transferase activity E. Inhibits initiation and causes misreading 6. The antibiotic tetracycline: A. Inhibits translocation B. Promotes chain termination C. Inhibits binding of charged tRNA to the ribosome D. Inhibits peptidyl transferase activity E. Inhibits initiation and causes misreading 7. Okazaki fragments: A. Are synthesized by DNA polymerase I B. Are complementary to leading template strand sequence C. Are complementary to lagging template strand sequence D. Are identical to lagging template strand sequence E. Are B form, double-helical DNA segments 8. Which enzyme relaxes DNA without using any energy and is critical for DNA replication? A.
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This document was uploaded on 11/04/2011 for the course BMB 401 at University of Miami.

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BMB401 F03 T4 KEY - I(Name have neither received nor given help BMB 401/506 Fall 2003 5 The antibiotic puromycin A Inhibits translocation B

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