BMB401 F05 T3

BMB401 F05 T3 - I, (Name) _ have neither received nor given...

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I, (Name) _________________________________________ have neither received nor given help BMB 401/506-Fall 2005 Third Examination November 8, 2005 KEY During the exam you should not be in possession of a beeper or a cellular phone. Please place your beeper and/or cellular phone in your book bag (after you turn it off!!!) and place the bag against the wall of the room. THESE ARE STANDARD SINGLE ANSWER MULTIPLE CHOICE QUESTIONS. THE POSSIBLE ANSWERS ARE LABELED A,B,C,D AND E. SELECT THE SINGLE BEST ANSWER AND MARK THE APPROPRIATE CIRCLE ON THE SCANTRON ANSWER SHEET. BUBBLE IN YOUR NAME AND ID# (C# ONLY PLEASE) . There are 37 questions. You will receive full credit for 36 correct answers. 1. Calculate moles ATP produced if β-hydroxybutyrate were to be the only end-product of palmitoyl CoA degradation. (Assume 4 moles of β-hydroxybutyrate are produced/mole palmitoyl CoA). A. 15 B. 18 C. 21 D. 23 E. 26 2. If the carbon in the bicarbonate used in malonyl CoA synthesis were labeled with 14 C in the synthesis of palmitate, where would the label be found in the reaction product? A. CO 2 B. C-16 of palmitate C. C-1 of palmitate D. Evenly distributed in palmitate carbons 1,3,5,7, ----- etc E. Evenly distributed in palmitate carbons 2,4,6,8, ----- etc 3. Which pair of substrates shown below can undergo a reversible transamination reaction? A. Acetoacetate and β-hydroxybutyrate B. Malonic acid and aspartic acid C. Oxaloacetate and α-ketoglutarate D. Pyruvic acid and glutamic acid E. None of the above 4. The addition of two carbon units to the growing fatty acid chain is driven by: A. Hydrolysis of UTP B. Oxidation of NADPH C. Reduction of NADP + D. Decarboxylation of malonyl CoA E. Hydrolysis of CTP 5. For mitochondrial acetyl CoA to be available in the cytoplasm for use in cholesterol biosynthesis, it must be transported from the mitochondria. What compounds are involved in the shuttle system for this transport? A. Citrate-malate-oxaloacetate B. Oxaloacetate-pyruvate C. Citrate-malate-pyruvate D. Citrate-malonate-pyruvate 6. The coenzyme used in the committed step in fatty acid biosynthesis is: A. Biotin B. NADH C. Pyridoxal phosphate D. Thiamine pyrophosphate E. FADH 2 7. Which ONE of the following statements concerning the activation of fatty acid is INCORRECT? A. It involves the formation of a high energy thiol ester bond B. Activation is concomitant with the hydrolysis of ATP to ADP + P i C. Activation is concomitant with the hydrolysis of ATP to AMP and pyrophosphate D. Further hydrolysis of pyrophosphate drives the activation reaction to completion
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BMB401 F05 T3 - I, (Name) _ have neither received nor given...

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