BMB401 F05 T4 - I, (Name) _ have neither received nor given...

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I, (Name) _________________________________________ have neither received nor given help BMB 401/506-Fall 2005 Fourth Examination December 1, 2005 KEY During the exam you should not be in possession of a beeper or a cellular phone. Please place your beeper and/or cellular phone in your book bag (after you turn it off!!!) and place the bag against the wall of the room. THESE ARE STANDARD SINGLE ANSWER MULTIPLE CHOICE QUESTIONS. THE POSSIBLE ANSWERS ARE LABELED A,B,C,D AND E. SELECT THE SINGLE BEST ANSWER AND MARK THE APPROPRIATE CIRCLE ON THE SCANTRON ANSWER SHEET. BUBBLE IN YOUR NAME AND ID# (C# ONLY PLEASE) . There are 35 questions. You will receive full credit for 34 correct answers. 1. If codons contained only two bases, what is the maximum number of amino acids that could be encoded by the four letter genetic code? A. 4 B. 8 C. 16 D. 20 E. 64 2. Mutations formed during DNA synthesis may be corrected by: A. DNA ligase B. The 5’ 3’ exonuclease activity of DNA polymerase C. The mismatch repair complex D. The sliding clamp E. Uracil glycosylase 3. What is/are the role(s) of transcription factors in gene expression? A. Activation of transcription B. Repression of transcription C. RNA polymerase II binding D. All of the above E. None of the above 4. What distinguishes germline engineering from somatic cell gene therapy? A. Engineered somatic cells are passed down to future generations. B. Germline engineering always uses nuclear transplantation, somatic engineering does not. C. Germline engineering changes the genome of every cell in a resulting organism. D. Germline engineering creates identical genetic clones. E. Somatic cell gene therapy is restricted to cells that line the somites. 5. Cloning by nuclear transplantation relies on all of the following EXCEPT… A. …a DNA-free nucleus. B. …a means of growing embryonic stem cells in culture. C. …a nucleus-free reprogramming cell. D. ...a source of somatic cells E. …reactivation of silenced genes. 6. Transcription… A. …initiates once per cell cycle. B. …is tightly coupled to translation in eukaryotes. C. …occurs in the nucleus of prokaryotes D. …requires a DNA primer. E. …terminates at stem-loop structures. 7. Which one of the following proteins is NOT involved in DNA repair? A. 5’ 3’ DNA exonuclease B. DNA polymerase I C. DNA ligase D. DNA topoisomerase I E. Uracil DNA glycosylase 8. Which of the following DNA sequences is a palindrome? A. 5’- AATTTTAA –3’ B. 5’- GAATATTC –3’ C. 5’- GAGTGAGT –3’ D. 5’- GATCCTAG –3’ E. 5’- TTAGCCTT –3’ 9. The below DNA sequence includes the beginning of a prokaryotic protein-coding gene. At which nucleotide position would translation of the messenger RNA copy begin and end, respectively? A.
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This document was uploaded on 11/04/2011 for the course BMB 401 at University of Miami.

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BMB401 F05 T4 - I, (Name) _ have neither received nor given...

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