T2.6_Fatty_acid_synthesis_and_regulation

T2.6_Fatty_acid_synthesis_and_regulation -...

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    ENERGY CONSERVATION FATTY ACID BIOSYNTHESIS NUTRITIONAL AND HORMONAL  REGULATION OF LIPOGENESIS                  Berg et al., CHAP 22
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LEARNING OBJECTIVES ORIGIN OF CYTOPLASMIC ACETYL CoA USED FOR THE  SYNTHESIS OF FATTY ACIDS ACETYL CoA CARBOXYLASE (ACC) AND FATTY ACID  SYNTHASE (FAS) CATALYZE KEY REACTIONS OF LONG- CHAIN FATTY ACID SYNTHESIS FROM ACETYL CoA ROLE OF BIOTIN AND PANTOTHENIC ACID DURING FATTY  ACID SYNTHESIS SYNTHESIS OF UNSATURATED FATTY ACIDS NUTRITIONAL AND HORMONAL FACTORS CONTROLLING  THE ACTIVITY AND CONTENT OF ACC AND FAS
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Structures of naturally occurring fatty  acids
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NUMBERING OF CARBON ATOMS  OF FATTY ACIDS
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Origin of cytoplasmic acetyl CoA
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Translocation of mitochondrial acetyl CoA  into the cytoplasm The following enzymatic steps are involved in the translocation of  mitochondrial acetyl CoA to cytosol: pyruvate dehydrogenase Pyruvate + CoA + NAD + acetyl CoA + NADH + CO 2 (i)                                                          pyruvate carboxylase Pyruvate + ATP + HCO 3 - oxaloacetate + ADP + P
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This document was uploaded on 11/04/2011 for the course BMB 401 at University of Miami.

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T2.6_Fatty_acid_synthesis_and_regulation -...

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