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Unformatted text preview: I, (Name) _________________________________________ have neither received nor given help and observed the Honor Code BMB 401 ©2009 Department of Biochemistry & Molecular Biology, University of Miami, reproduction prohibited. Page 1 of 4 BMB 401/506-Fall 2008 Exam 3 Form 1 Thursday November 5, 2009 During this exam you should not be in possession of any electronic equipment (beeper, cellular phone, earphone, iPods, calculators, etc.), books and papers, other than the test. Please place all these materials in your book bag (after you turn them off!!) and place the bag against the wall of the room. THESE ARE STANDARD ANSWER MULTIPLE CHOICE QUESTIONS. THE POSSIBLE ANSWERS ARE LABELED A, B, C, D AND E. SELECT THE SINGLE BEST ANSWER AND MARK THE APPROPRIATE CIRCLE ON THE SCANTRON ANSWER SHEET. Bubble in your name, form# and ID# (C# please) and write your seat number. There are 36 questions. You will receive full credit for 35 correct answers. 1. Mammalian fatty acid synthase has all of the following characteristics EXCEPT: A. Is classified as a multi-enzyme complex B. As many as seven different catalytic centers are present on its single polypeptide chain C. The monomer of this multi-enzyme complex is catalytically active D. Synthesis of long-chain fatty acids occurs only when the enzyme is a dimer E. None of the above 2. Mammalian acetyl CoA carboxylase has all of the following characteristics EXCEPT: A. All the catalytic and regulatory sites are housed on a relatively large (~ 260 -280 kDa) single polypeptide chain B. The protomer polymerizes in the presence of citrate C. The polymer of the mammalian enzyme is catalytically active D. The enzyme is inhibited by palmitoyl CoA E. Phosphorylation mediated by an AMP-activated protein kinase activates the enzyme 3. During fatty acid synthesis, fatty acid degradation is inhibited. It is because: A. Conversion of long-chain fatty acids to their acyl- CoA derivatives is blocked B. Released fatty acids from circulating chylomicrons...
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This document was uploaded on 11/04/2011 for the course BMB 401 at University of Miami.
- Fall '09