Clonal selection hypothesis

Clonal selection hypothesis - 3 Upon contacting its...

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Clonal selection hypothesis (Jerne and Burnet): The clonal selection hypothesis attempts to explain the findings described above by suggesting the following: 1. Animals contain numerous cells called lymphocytes, 2. Each lymphocyte is responsive to a particular antigen by virtue of specific surface receptor molecules,
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Unformatted text preview: 3. Upon contacting its appropriate antigen, the lymphocyte is stimulated to proliferate (clonal expansion) and differentiate, 4. The expanded clone is responsible for the secondary response (more cells to respond) while the differentiated ("effector") cells secrete antibody,...
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This note was uploaded on 11/05/2011 for the course BIOLOGY MCB2010 taught by Professor Jessicadigirolamo during the Fall '10 term at Broward College.

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