CONTROL7 - Picornaviruses commonly produce subclinical...

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CONTROL: Sanitary: Quarantine of diseased individuals. Immunological: Vaccination of all individuals. Chemotherapeutic: None. Picornaviruses VIRUS: Picornaviruses: Enteroviruses, Rhinoviruses GENERAL CONCEPTS: Picornaviruses are small, nonenveloped viruses containing a single positive strand RNA genome. They possess an icosahedral symmetry. Picornaviruses are divided into two groups; the Enteroviruses (Poliovirus, Coxsackievirus and Echovirus) and the Rhinoviruses. There are about 63 serotypes of Enterovirus and more than 100 serotypes of Rhinovirus.
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Unformatted text preview: Picornaviruses commonly produce subclinical infections; acute disease may range from minor illness to paralytic disease. • The Enteroviruses enter via the intestinal tract and attach to receptors on intestinal epithelia. During this alimentary phase, the virus replicates in cytoplasm. They then spread into the lymphatic circulation (lymphatic phase) and then to the bloodstream (viremic phase). The viremic phase generally marks the end of the infection but an occasional neurologic phase can lead to more severe and permanent problems....
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