DIAGNOSI8 - • Sanitary As with other sexually transmitted...

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DIAGNOSIS: Clinical: The clinical manifestations of the treponematoses are generally characteristic and readily identified. Laboratory: Darkfield examination of material from a chancre can show the presence of spirochetes. Immunological techniques including fluorescent treponemal antibody (FTA) or T. pallidum immobilization (TPI) can be of great assistance in observing the organisms. The Wassermann test looks for the presence of antibody against cardiolipin. Many other tests are also available. CONTROL:
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Unformatted text preview: • Sanitary: As with other sexually transmitted diseases (STDs), use of a condom helps prevent infection. • Immunological: None are available. • Chemotherapeutic: Benzathine penicillin (long acting) or penicillin G are the drugs of choice. One must be aware of a possible Jarisch-Herxheimer reaction following treatment of secondary or tertiary syphilis, however. The rapid release of treponemal antigens after lysis by penicillin can cause hypersensitivity reactions in some persons....
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