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Unformatted text preview: kidneys. Multiplication in the kidneys leads to shedding in the urine (leptospiruric phase). This may persist for weeks, months or years. Leptospira produce no known exo- or endotoxins. Damage to the endothelial lining of capillaries and renal failure are the most common reasons for death. Occasionally the central nervous system may become involved. The host immune response is probably responsible for lesions associated with late phase of disease. This is suggested because antibiotics are ineffective after symptoms have persisted for more than 4 days...
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This note was uploaded on 11/05/2011 for the course BIOLOGY MCB2010 taught by Professor Jessicadigirolamo during the Fall '10 term at Broward College.
- Fall '10