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DISTINCTIVE PROPERTI24 - by Pseudomonas This product causes...

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DISTINCTIVE PROPERTIES: Pseudomonads are Gram negative rods. They are motile, nonfermentative aerobes that can utilize acetate for carbon and ammonium sulphate for nitrogen. Many species are resistant to high salt, dyes, weak antiseptics and most antibiotics. P. aeruginosa can grow at 42°. Pseudomonas possesses the LPS endotoxin characteristic of other Gram-negative bacteria and displays O and H antigens. Pseudomonas produces many exoenzymes including hemolysins, leukocidins and proteases. In addition, a toxin called Toxin A is the most toxic product produced
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Unformatted text preview: by Pseudomonas . This product causes the ADP-ribosylation of translation factor EF-2, producing ADP-ribosyl-EF-2. The effect of this enzymatic activity is the loss of host cell protein synthesis capability. This mechanism is identical to that produced by diphtheria toxin. • Also, a protein called exoenzyme S is another ADP-ribosyltransferase, transferring the ADP-ribose from NAD to other proteins (not EF-2). • Pseudomonas has an antiphagocytic polysaccharide slime layer and many strains produce pigments, some which are fluorescent....
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