DNA Viruses - encoding structural proteins that enclose the...

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DNA Viruses Retrovir uses mRNA +RNA RNA/D NA Reverse Transcrip tase Proteins (replicat ive) dsDN A Proteins (structu ral) Integrati on into Host Genome dsDNA dsDNA +RNA Proteins Progeny Virus Progeny Virus Most DNA viruses utilize a standard semi- conservative mode of replication. Often, the DNA is immediately transcribed by host proteins to produce mRNAs that encode virus-specific transcription factors. These factors lead to selective transcription of genes involved in DNA synthesis, and genes encoding additional transcription factors. This final set of factors produces mRNAs
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Unformatted text preview: encoding structural proteins that enclose the newly-synthesized DNA, producing progeny virions. Retroviruses have a unique means of replication. The viral RNA is first reverse transcribed by a viral protein (reverse transcriptase, RT) to produce an RNA/DNA hybrid duplex. RT then removes the RNA strand while synthesizing a new DNA strand to produce dsDNA, which then integrates into the host genome. From this location, progeny RNA molecules and structural proteins are combined to produce new viral particles....
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