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GENERATION OF ANTIBODY DIVERSITY - line cells into B-cells...

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GENERATION OF ANTIBODY DIVERSITY The immune system has the capacity to recognize and respond to about 10 7 different antigens. This extreme diversity can be generated in at least three possible ways: 1. Multiple genes in the germ line DNA. 2. Variable recombination during the differentiation of germ
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Unformatted text preview: line cells into B-cells. 3. Mutation during the differentiation of germ line cells into B-cells. It is known that all three of these possibilities take place to produce antibody diversity. The following figures illustrate these possibilities:...
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