HOST DEFENS10 - major South America for variola minor...

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HOST DEFENSES: Antiviral antibody is protective. Hyperimmune serum can prevent disease. The cell-mediated response is also important, however, since individuals with hypogammaglobulinemia still recover. EPIDEMIOLOGY: Before eradication, Asia and India were endemic for variola
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Unformatted text preview: major; South America for variola minor. DIAGNOSIS: • Clinical: The characteristic lesions with their centrifugal and synchronous development are diagnostic. • Laboratory: Electron microscopy of crusts can reveal the intracytoplasmic inclusions....
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