HOST DEFENSE3 - HOST DEFENSES The normal host resists...

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HOST DEFENSES: The normal host resists streptococcal infection; they are often secondary invaders. The capsule of S. pyogenes is poorly immunogenic; anti-M protein Abs are important in host defense. The capsule of S. pneumoniae is very immunogenic; anti- capsule Abs are opsonizing, enhancing phagocytosis. Pneumococcal infections occur most often in debilitated persons (alcoholics, elderly, those with underlying disease). EPIDEMIOLOGY: These organisms are widely distributed in nature.
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