HOST DEFENSE4 - opsonization and the action of complement...

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HOST DEFENSES: Staphylococci have a long association with humans and make up a major portion of our skin flora. Because of this relationship, there are many factors acting both ways. Staphylococci generally resist host defenses. Antibody may help in certain circumstances but protein A prevents
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Unformatted text preview: opsonization and the action of complement. EPIDEMIOLOGY: • These organisms are ubiquitous. Prior to 1950, most staphylococci were sensitive to penicillin; now, most are resistant (hospital strains). Synthetic penicillins have been very useful but now resistance to vancomycin is spreading....
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