HOST DEFENSE5 - may contain neutralizing factors as well...

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HOST DEFENSES: Parainfluenza: Interferon and neutralizing IgA are important but IgA is often short lived. Mumps: Interferon limits viral spread while IgM and IgG are protective. Long lasting IgG affords life-long immunity. Measles: Interferon affects viral spread but the cell- mediated response is associated with recovery (disease is more severe in persons with a T-cell immunodeficiency). Life long persistence of IgG affords protection. RSV: Interferon, age, immune competence and neutralizing IgA (short lived) all contribute to host defense. Breast milk
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Unformatted text preview: may contain neutralizing factors as well. EPIDEMIOLOGY: • Parainfluenza: Found worldwide, Parainfluenza affects mostly children. The virus is endemic in some areas and epidemic at times. The source for infections is the respiratory tract of humans. Disease is contagious for 3-16 days, transmission is person to person or by droplets. At 5 years of age, about 90-100% have antibodies against type 3, about 74% for type 1 and about 58% for type 2....
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