HOST DEFENSE9 - relate to the host immune response The...

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HOST DEFENSES: Hepatitis A: Antibody usually develops late in the infection; IgM after a week, IgG later. These help to clear virus from the body via complement and antibody- dependent cell-mediated cytotoxicity, which may account for some of the liver damage. Hepatitis B: Antibody and the cell-mediated responses are induced but do not seem to protect against infection and probably cause autoimmune responses (liver damage may
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Unformatted text preview: relate to the host immune response). The possibility of immune complexes with surface antigen can also lead to immune complex disease. • Hepatitis C: Little is known about host defenses against this agent but immune serum does not seem to be an effective prophylactic remedy. Probably a combination of humoral and cell-mediated defenses are important....
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