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Human genetics is retrospective (vs prospective). Human
geneticists cannot
test hypotheses prospectively. The mouse
provides a prospective surrogate.
• Can’t do selections
• Meager amounts of data Human geneticists typically rely upon
statistical
arguments as opposed to overwhelming
amounts of data in drawing connections between
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Unformatted text preview: genotype and phenotype. • Highly dependent on DNA-based maps and DNA-based analysis The unique advantages of human genetics: • A large population which is self-screening to a considerable degree • Phenotypic subtlety is not lost on the observer • The self interest of our species...
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- Fall '10
- JessicaDigirolamo
- Microbiology, Genetics, Evolution, Genotype-phenotype distinction
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