It is important to note that once a map distance between two genetic markers has been established th

It is important to note that once a map distance between two genetic markers has been established th

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It is important to note that once a map distance between two genetic markers has been established this distance can be used to calculate the expected numbers of each type of progeny. For example, if you know that two mutations are 12 cM apart then you should expect that 6% of the progeny from a cross will be of each of recombinant class. Things get interesting when we make several pairwise crosses between genes on the same chromosome. We can use this data to construct a
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Unformatted text preview: G Genetic maps have the following properties: i Distance is proportional to frequency of crossover classes (this approximation actually only holds for short distances of <20 cM) i Distances are approximately additive: mapped points fall on a line. i Maps are internally consistent and concise. (The first genetic map was constructed in 1911 by Alfred Sturtevant when he was asophomore student in Morgan’s lab)...
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This note was uploaded on 11/05/2011 for the course BIOLOGY MCB2010 taught by Professor Jessicadigirolamo during the Fall '10 term at Broward College.

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