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Last time we discussed how to measure the distance between two genes on the X chromosome

Last time we discussed how to measure the distance between two genes on the X chromosome

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Last time we discussed how to measure the distance between two genes on the X chromosome. To do this we used the trick of looking only at male progeny so the genotype of the X chromosome could be scored directly since these flies only carry one copy of the X. For autosomes, we can have the same ability to score all recombinant classes by crossing to a homozygous recessive individual. This is known as a test-cross. Consider the recessive traits vestigial wings and short bristles that are specified by two different
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Unformatted text preview: genes on the same autosome (non-sex chromosome). + + v s x O O v s + + ↓ v s All F1: + + The F1 flies are heterozygous for both genes so we are in position to see how often_crossovers between these chromosomes occur in meiosis by doing a test-cross. O v s v s x O + + v s ↓ (Note that the progeny v s 458 have distinct phenotypes) v s v s 442 + + v + v s 47 (crossover classes) +++++ shshshshsh 53 v s 100 The distance between vvvvv and sssss = 100 x = 10 cM 1000...
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