M and N are different blood antigens specified by alleles of the same gene

M and N are different blood antigens specified by alleles of the same gene

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
M and N are different blood antigens specified by alleles of the same gene. The antigens are codominant so a simple blood test can distinguish the three possible genotypes. f( M /M ) = 0.83, f( M /n ) = 0.16, f( N /N ) = .01 p = f( M ) = .83 + .08 = 0.91 q = f( N ) = .01 + .08 = 0.09 Note: we can get both p and q with just two of the genotype frequencies because the three genotype frequencies must total to a frequency of 1.0: f( M /M ) + f( M /N ) + f(
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: N /N ) = 1 Now let's think about how the inverse calculation would be performed. That is, how to derive the genotype frequencies from the allele frequencies. To do this we must make an assumption about the frequency of mating of individuals with different genotypes. If we assume that the gametes mix at random, we can calculate the compound probabilities of obtaining each possible combination of alleles....
View Full Document

This note was uploaded on 11/05/2011 for the course BIOLOGY MCB2010 taught by Professor Jessicadigirolamo during the Fall '10 term at Broward College.

Ask a homework question - tutors are online