Unformatted text preview: body). Complications are mainly bacterial superinfection but other rare complications (e.g. SSPE) can occur. • RSV: The RS virus initiates a local infection in the upper or lower respiratory tract but illness varies with age and previous experience. The virus infects ciliated epithelia of the nose, eye and mouth and remains generally confined. Virus spreads extracellularly and by fusion. Severe disease may present as bronchiolitis, pneumonia or croup, particularly in infants. Some evidence suggests that there are possible immunopathologic mechanisms involved....
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- Fall '10
- Microbiology, lower respiratory tract, systemic infection