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Unformatted text preview: 1. Chronic persistent: Infections are generally asymptomatic with a mild elevation of serum alanine transaminase (ALT) and little liver fibrosis. 2. Chronic active: Infections produce jaundice with elevated ALT levels, liver damage and cirrhosis. Liver failure may predispose those affected to cancer . • Hepatitis C: HCV may also produce a persistent carrier state, a higher level of chronic disease and cirrhosis. At least 50% of HCV infections result from blood transfusion. • The following table outlines some of the differences between the Hepatitis viruses: Hepatitis A Hepatitis B Hepatitis C Genome +RNA DNA +RNA Onset Abrupt Insidious Insidious Transmission Fecal-Oral Parenteral Parenteral Incubation (days) 15-40 60-180 28-112 Asymptomatic infection usual common common Carrier State no yes yes Chronicity 0% 10% 30-60% Sequelae no cirrhosis cirrhosis...
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- Fall '10
- Microbiology, Hepatitis C, liver damage, Carrier state, Hepatitis B Hepatitis