Poxviruses - morphology and replicate in the host...

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Poxviruses VIRUS: Poxviruses (Orthopoxviruses): Smallpox GENERAL CONCEPTS: A passage from T. B. Macaulay's The History of England from the Accession of James II , volume IV, serves to preface this page describing the disease smallpox: "The smallpox was always present, filling the churchyards with corpses, tormenting with constant fears all whom it had stricken, leaving on those whose lives it spared the hideous traces of its power , turning the babe into a changeling at which the mother shuddered, and making the eyes and cheeks of the betrothed maiden objects of horror to the lover." The Poxviruses contain a dsDNA genome, have a complex
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Unformatted text preview: morphology and replicate in the host cytoplasm. Poxviruses cause localized and generalized infections in humans and animals. Smallpox was the major human disease agent but it was officially declared eradicated by the World Health Organization (WHO) in 1980. Smallpox is transmitted via the respiratory route. In the body, it is spread by a transient viremia to internal sites, and then a second viremia to the skin where the characteristic lesions erupt. The lack of an animal reservoir made eradication of human disease possible....
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Poxviruses - morphology and replicate in the host...

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