REGULATION OF THE HUMORAL RESPONSE

REGULATION OF THE HUMORAL RESPONSE - possibly involving...

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REGULATION OF THE HUMORAL RESPONSE Regulation of the immune response is possibly mediated in several ways. First, a specific group of T-cells, suppressor T-cells, are thought to be involved in turning down the immune response. Like helper T-cells, suppressor T-cells are stimulated by antigen but instead of releasing lymphokines that activate B-cells (and other cells), suppressor T-cells release factors that suppress the B-cell response. While immunosuppression is not completely understood, it appears to be more complicated than the activation pathway,
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Unformatted text preview: possibly involving additional cells in the overall pathway. Other means of regulation involve interactions between antibody and B-cells. One mechanism, "antigen blocking", occurs when high doses of antibody interact with all of the antigen's epitopes, thereby inhibiting interactions with B-cell receptors. A second mechanism, "receptor cross linking", results when antibody, bound to a B-cell via its Fc receptor, and the B-cell receptor both combine with antigen. This "cross-linking" inhibits the B-cell from producing further antibody....
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This note was uploaded on 11/05/2011 for the course BIOLOGY MCB2010 taught by Professor Jessicadigirolamo during the Fall '10 term at Broward College.

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REGULATION OF THE HUMORAL RESPONSE - possibly involving...

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