retinitis pigmentosa - families • autosomal dominant...

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retinitis pigmentosa (RP): • degeneration of retina (accompanied by deposits of pigment in retina) progressive visual impairment blindness • population prevalence of 1/3,000 • one of most common causes of blindness among middle aged in developed countries • autosomal recessive inheritance in 84% of affected
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Unformatted text preview: families • autosomal dominant inheritance in 10% of affected families • X-linked recessive inheritance in 6% of affected families • At least 66 different genetic loci implicated but RP appears to be result of a single gene mutation in any given family, at least in most cases NON-ALLELIC HETEROGENEITY...
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This note was uploaded on 11/05/2011 for the course BIOLOGY MCB2010 taught by Professor Jessicadigirolamo during the Fall '10 term at Broward College.

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