Trisomy 21 Down Syndrome

Trisomy 21 Down Syndrome - maternal alleles for SSR 21.1...

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Trisomy 21 Down Syndrome nondisjunction = failure of chromosomes to separate normally during cell division Nondisjunction can occur during How could you figure out whether nondisjunction for chromosome 21 had occurred during meiosis or mitosis? What can you conclude? At least two things: 1. The presence in the affected child of two different
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Unformatted text preview: maternal alleles for SSR 21.1 indicates that recombination between the two chromosome 21s in the mother prior to nondisjunction. nondisjunction occurred before fertilization (in meiosis) in the mother. 2. There has been...
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