What does it mean - alternative splicing to produce...

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What does it mean “Genes Have Introns”. This represents one of the fundamental organizational differences between prokaryotic and eukaryotic genes. Eukaryotic genes turn out to be int errupted with long DNA sequences that do not encode for protein…these “ int ervening sequences” are called int rons. The DNA segments that are ultimately ex pressed as protein, i.e., the DNA sequence that contains triplet codon information, are called ex ons. The intronic sequences are removed from the primary transcript by splicing. A major consequence of this arrangement is the potential for
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Unformatted text preview: alternative splicing to produce different proteins species from the same gene and primary transcript. This gives the potential for tremendous amplification of the complexity of mammals (and other eukaryotes) through many more thousands of possible proteins. Note that lower eukaryotes such as the yeast S. cerevisiae only have ~ 5% of their genes interrupted by introns, but for multicellular organisms, like humans, >90% of all genes are interrupted by anywhere between 2 and 60 introns, but most genes have between 5 and 12 introns....
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