3 - co-activator and co-supressor proteins CLICK FIGURE FOR...

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3. Intracellular Receptors - Steroids a. Steroids are Membrane soluble - kept in solution by binding/carrier proteins b. Nuclear binding proteins = receptors - DNA regulation: H + R > HR > DNA binding > enhance transcription - Steroid hormone receptors are homodimers in mammals (vertebrates?) and heterodimers in insects. - Further regulation through interaction between HR and
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Unformatted text preview: co-activator and co-supressor proteins. CLICK FIGURE FOR LARGER IMAGE 4. Responses: a. hormones release hormones b. alter existing proteins: p hysiologica l change / metabolic change - ^ BP > aldosterone > ^ NaCl reabsorption distal tubule c. make new proteins - gene expression E. Inactivation: Metabolic Conversion...
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