Simulation - structure- like a switch - external activation...

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Simulation - regulation of release - triggered release a. "sensory" input b. hormonal regulation c. neural regulation D. Target activation - Signal Transduction 1. Concept of Target Cells : Target Specific Receptors a. since hormone enters blood every cell is exposed b. only specific "target" cells respond c. only "target" cells contain receptors to recognize hormone 2. Cell Surface Receptors - Second Messenger Systems CLICK FIGURE FOR LARGER IMAGE CLICK FIGURE FOR LARGER IMAGE a. Lipophobic Hormones : no crossing of membrane b. Membrane Bound Receptor Proteins - external binding site highly specific to given hormone
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Unformatted text preview: structure- like a switch - external activation leads to internal activation c. Second messengers- "Second messenger" is an historic term-- stimulate a cell with a hormone-- observe the production of an intracellular chemical-- the intracellular chemical became known as 2nd Messenger-- excitement because only a few identified 2nd Messenger chemicals but huge number of cellular responses throughout the body-- 2nd Messengers include cAMP, cGMP, Ca++, NO, CO-- specific enzymes are activated to produce 2nd Messengers...
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Simulation - structure- like a switch - external activation...

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