The Endocrine System I Chapter 35

The Endocrine System I Chapter 35 - b. steroids: 4....

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The Endocrine System I Chapter 35, 10/25/96 I. Hormones / Target Cells A. Chemical Signals -- Chemoreception B. Coordination requires communication: chemoreception C. "hormon" - "excite": "A chemical secreted by cells in one part of the body that is transported in the bloodstream to other parts of the body, where it affects particular target cells." D. History: Plants and Bugs II. Hormone Action: triggered synthesis and/or release - target stimulation - clearance A. Hormones come from secretory cells 1. endocrine glands 2. neurohemal organ B. Hormones: peptides; modified amino acids; steroids; modified fatty acids C. Synthesis and release - triggered 1. Secretory Cells 2. Gland and Cell Types a. Exocrine Glands b. Endocrine Glands c. Neurosecretory Cells 3. Mechanism of release a. hormones that are not steroids or lipids
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Unformatted text preview: b. steroids: 4. Simulation - regulation of release - triggered release D. Target activation - Signal Transduction 1. Concept of Target Cells : Target Specific Receptors 2. Cell Surface Receptors - Second Messenger Systems a. Lipophobic Hormones : no crossing of membrane b. Membrane Bound Receptor Proteins c. Second messengers d. G-proteins e. Second Messenger activates cellular response f. Detail Example 1. cAMP pathway g. Detail Example 2. IP3 and Calcium h. others Examples, all hormone receptor mediated, could include. .. i. SIGNAL AMPLIFICATION 3. Intracellular Receptors - Steroids a. Steroids are Membrane soluble b. Nuclear binding proteins = receptors 4. Responses: a. hormones release hormones b. alter existing proteins: c. make new proteins E. Inactivation: Metabolic Conversion...
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This note was uploaded on 11/06/2011 for the course BIO BSC1010 taught by Professor Gwenhauner during the Fall '10 term at Broward College.

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The Endocrine System I Chapter 35 - b. steroids: 4....

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