Lecture14+full+notes

Lecture14+full+notes - Slide 1 Frontal Lobe Slide 2 Review...

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Slide 1 Frontal Lobe
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Slide 2 Review Questions 1. What is the general term that captures the majority of frontal lobe functioning? 2. What are the 3 main subdivisions of the frontal lobe? 3. What are the anatomical subdivisions of the prefrontal cortex? 4. Describe the connections & main functions of the: dlpfc, secondary motor ctx, primary motor ctx 5. What are the 3 main functions of the frontal lobe in organizing sequential behavior?
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Slide 3 Frontal Lobe: Outline I. Introduction II. Anatomy & Connections III. Theory of Function IV. Effects of Damage
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Slide 4 I. The Frontal Lobes: Overview Damage rarely produced immediate and dramatic changes in sensation, perception, memory, motor function, & language Success, timing, & appropriateness of behavior depend on the integrity of the frontal lobes Executive function : dictating how goal-oriented behavior is controlled; primary role of frontal lobes Includes the initiation, inhibition and elaboration of behavior Planning, organizing, problem solving, and executing the volitional aspects of his/her behavior Maturation continues through adolescence Emotional maturation also continues through adolescence & relies on inhibitory mechanisms Decline occurs in old age
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Slide 5 II. Anatomy of the Frontal Lobes • All tissue anterior to central sulcus • Three main subdivisions (primarily functional distinctions): – Motor (primary) – Premotor (“before motor”) - aka secondary motor cortex – Prefrontal Cortex (“in front of the front”)
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Slide 6 Orbitofrontal cortex Medial Prefrontal Cortex (PFC) Premotor & Supplementary Motor Area Frontal lobe described in terms of planar perspectives: Basilar orbital (A) Medial (B) Dorsolateral (C) Recently, the anterior cingulate cortex has been incorporated into a general functional definition A B C Dorsolateral PFC Anterior cingulate Although anterior cingulate is technically a subcortical structure, is integral to functional aspects of frontal lobe function, so is now lumped in
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Slide 7 Orbitofrontal cortex Medial PFC Premotor/Suppl. A B C 10 46 9 9 9 8 8 45 44 6 6 6 45 47/12 10 11 13 14 4 4 4 6 8 9 10 13 13 Premotor/Motor areas of frontal lobe described in terms of Petrides & Pandya numbers: Area 4 (primary motor cortex) Secondary Motor Cortex: Premotor/Supplementary cortex lateral and medial area 6 Medial area 6 (also known as supplementary motor cortex) area 44 (Broca‟s area) frontal eye field (area 8)
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Slide 8 Frontal Lobe Frontal Lobe Frontal Lobe A C 10 46 9 9 9 8 8 45 44 6 6 Prefrontal cortex (PFC) subdivided in terms of Petrides & Pandya numbers: Dorsolateral PFC : areas 9 & 46 Inferior (ventral) PFC (AKA orbitofrontal ctx ): areas 10-14 Medial frontal ctx : areas 25 & 32; sometimes considered part of anterior cingulate ctx even though it receives dorsomedial thalamic projections 6 45 47/12 10 11 13 14 4 4 4 6 8 9 10 13 13 PREFRONTAL CORTEX Regions of the PREFRONTAL CORTEX
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Slide 9 Prefrontal Cortex (PFC) Major focus of contemporary research Originally identified as the target for the
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Lecture14+full+notes - Slide 1 Frontal Lobe Slide 2 Review...

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