Lecture22+full+notes

Lecture22+full+notes - Slide 1 Cerebral Lateralization...

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Slide 1 Cerebral Lateralization (Asymmetry) of Function Phantoms: Ch 7 Case study MS: 25 year-old epileptic & mother of 2. Her seizures were well controlled w/ meds until after the birth of her 2 nd child, after which she suffered uncontrolled seizures at least 1/month. Scans revealed that she had a long-standing cyst in her left temporal lobe. She decided to have it surgically removed in hopes of eliminating the seizures. All seemed to have gone well, with seizures cured, until she developed an antibiotic-resistant infection. Within a few days, she suffered extensive damage to her left hemisphere. She was left with global aphasia – the inability to either produce or understand language. For weeks, the only words she could say were “I love you.” Despite her severe language problems, she was able to understand & appreciate music. She could sing songs she knew prior to her surgery, and while her ability to learn the words to new songs was impaired, she could learn new tunes & hum along. Thus illustrates the dissociation of hemispheric function: her language was severely impaired but she retained her musical skills.
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Slide 2 Review Questions 1. What are the 5 main dimensions of schizophrenia symptoms? 2. What does imaging reveal about the neural activity of schizophrenics? 3. Auditory hallucinations are associated w/ activation of which areas of the brain? 4. List some structural & biochemical abnormalities associated w/ schizophrenia. 5. What are the potential causes of schizophrenia? 6. 7. Which areas of the brain are implicated in depression? 8. Describe the sensitization model of bipolar disorder.
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Slide 3 Commonly Encountered Terms • Laterality • Hemispheric specialization • Cerebral Asymmetry (anatomical or functional) • Cerebral (or hemispheric) dominance One of the most intriguing aspects of human brain organization is cerebral asymmetry – that the left & right hemispheres of our brains have partly separate functions! All these various terms are used to describe the same phenomenon – that each half of our brains does slightly different things. We‟ve already seen this very apparently when we discussed stroke, vision, movement – the right side of our brain controls movement on the left side of the body & the left side of the brain controls movement on the right side. But it‟s more subtle & complicated than that very simple distinction.
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Slide 4 Historical Antecedents of Apparent Cerebral Dominance • 1836 : French physician, Marc Dax, reported on language deficits observed only in those presenting with damage to left side of the brain – Report had little impact since localization of function theories were not popular at the time • 1864 : Paul Broca reported that post mortem examination of 7 aphasic patients showed damage in the inferior prefrontal ctx of the left hemisphere • Early 1900‟s : observations were made that apraxia typically occurred in response to left hemisphere damage
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This note was uploaded on 11/05/2011 for the course 830 310 taught by Professor Joannehash-converse during the Spring '11 term at Rutgers.

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Lecture22+full+notes - Slide 1 Cerebral Lateralization...

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