MOL CLASS 23 - Enzymes and Drug Design (Part 2) (class notes S11)

MOL CLASS 23 - Enzymes and Drug Design (Part 2) (class notes S11)

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Class 23 – Enzymes and Drug Design (2) Molecules of Life – Spring 2011 1 NATURAL SCIENCE II: MOLECULES OF LIFE Spring 2011 Class 23 – Wednesday, April 27 Enzymes and Drug Design – Part 2 Reading: Chapter 20, pp. 16 – 25 Next class: Benderly – Experimental Drugs on Trial OUTLINE (1) Announcements & review (2 HIV protease inhibitor drugs 1 (2) (3) The end of AIDS? (4) HIV mutations and drug resistance (5) Aspirin & Vioxx revisited (6) How are new drugs tested and approved? ANNOUNCEMENTS
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Class 23 – Enzymes and Drug Design (2) Molecules of Life – Spring 2011 2 REVIEW E E I 3 I DESIGNING AN HIV PROTEASE INHIBITOR 4
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Class 23 – Enzymes and Drug Design (2) Molecules of Life – Spring 2011 3 CRIXIVAN: An HIV protease inhibitor 5 HIV PROTEASE INHIBITOR DRUGS Kaletra (lopinavir) 6 Agenerase (amprenavir) Reyataz (atazanavir)
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Class 23 – Enzymes and Drug Design (2) Molecules of Life – Spring 2011 4 THE END OF AIDS? The power of the newest drugs, called protease inhibitors, and the even greater power of those in the pipeline, is such 0 10 1980 1985 1990 1995
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This note was uploaded on 11/07/2011 for the course MAP V55.0310.0 taught by Professor Tracejordan during the Spring '11 term at NYU.

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MOL CLASS 23 - Enzymes and Drug Design (Part 2) (class notes S11)

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