MOL CLASS 18 - Protein Architecture (class notes S11)

MOL CLASS 18 - Protein Architecture (class notes S11) -...

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Class 18 – Protein Architecture Molecules of Life – Spring 2011 1 NATURAL SCIENCE II: MOLECULES OF LIFE Spring 2011 Class 18 – Wednesday, April 6 Protein Architecture Reading: Chapter 17 Next class: Midterm Exam 2 OUTLINE (1) Announcements & review (2 Structure and diversity of amino acids 1 (2) (3) Making a peptide bond (4) Principles of protein architecture primary, secondary, tertiary, quaternary (5) Sickle cell anemia – a molecular disease ANNOUNCEMENTS 2
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Class 18 – Protein Architecture Molecules of Life – Spring 2011 2 REVIEW 3 STRUCTURE OF AMINO ACIDS 4
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Class 18 – Protein Architecture Molecules of Life – Spring 2011 3 AMINO ACIDS ARE CHIRAL MOLECULES 5 DIVERSITY OF AMINO ACID SIDECHAINS There are 20 TYPES OF AMINO ACID that are commonly found in proteins. Amino acids differ in the chemical structure of their SIDECHAINS (R). We can organize the 20 sidechains into four chemical groups : 6
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Class 18 – Protein Architecture Molecules of Life – Spring 2011 4 7 8
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Class 18 – Protein Architecture Molecules of Life – Spring 2011 5 MAKING A PEPTIDE BOND 9 THE PEPTIDE BOND IS PLANAR 10
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Class 18 – Protein Architecture Molecules of Life – Spring 2011 6 FOLDING THE POLYPEPTIDE CHAIN 11 PROTEIN ARCHITECTURE 12
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This note was uploaded on 11/07/2011 for the course MAP V55.0310.0 taught by Professor Tracejordan during the Spring '11 term at NYU.

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MOL CLASS 18 - Protein Architecture (class notes S11) -...

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