MOL CLASS 12 - Molecules to Cells - Part 2 (class notes S11)

MOL CLASS 12 - Molecules to Cells - Part 2 (class notes...

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1 NATURAL SCIENCE II: MOLECULES OF LIFE Spring 2011 Class 12 – Wednesday, March 9 From Molecules to Cells (Part 2) Reading: Chapter 8, pp. 23 – 42 + two articles Next class: Chapter 14 , pp. 1 – 15 (DNA) OUTLINE (1) Announcements & review (2) A prokaryotic cell (3) Macromolecular complexes (4) Killing bacteria with antibiotics (5) The problem of antibiotic resistance (6) A eukaryotic cell and its organelles
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2 ANNOUNCEMENTS
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3 REVIEW
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4 A PROKARYOTIC CELL
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5 MACROMOLECULAR COMPLEXES
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6 KILLING BACTERIA WITH ANTIBIOTICS The word antibiotic ” means “ anti-life .” So how does an antibiotic kill bacteria selectively without killing our own cells?
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7 MAKING THE BACTERIAL CELL WALL
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WHAT IS PENICILLIN? 8 Alexander Fleming - 1928 molecular structure of penicillin G
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9 HOW DO PENICILLINS WORK?
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Unformatted text preview: methicillin-resistant Staphylococcus aureus (MRSA) 10 THE PROBLEM OF ANTIBIOTIC RESISTANCE multiple drug-resistant tuberculosis (MDR-TB) and extreme drug-resistant tuberculosis (XDR-TB) 11 Christopher T. Walsh and Michael A. Fischbach, “New Ways to Squash Superbugs” Scientific American – July 2009 12 Christopher T. Walsh and Michael A. Fischbach, “New Ways to Squash Superbugs” Scientific American – July 2009 13 WHERE WILL NEW ANTIBIOTICS COME FROM? 14 A EUKARYOTIC CELL 15 CELL NUCLEUS 16 RIBOSOME ENDOPLASMIC RETICULUM 17 MITOCHONDRION 18 THE CELL MEMBRANE (1) – phospholipid bilayer 19 THE CELL MEMBRANE (2) – fluid mosaic model 20 CROSSING THE CELL MEMBRANE...
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