Ch05.2-05Oct

Ch05.2-05Oct - Wednesday 5 October 2011 This lecture was...

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Chapter 4: The Generation of Lymphocyte Antigen Receptors MBB/HSCI 426, MBB 726 Immune System I Monday & Wednesday 3 & 5 October 2011 This lecture was taken from: Chapter 5, pp. 157-197
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Chapter 4: The Generation of T-Lymphocyte Antigen Receptors MBB/HSCI 426, MBB 726 Immune System I Wednesday 5 October 2011 This lecture was taken from: Chapter 4, pp. 169-173
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TREC
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Appendix: Whole Mouse Experiments and The Generation of Transgenic Mice MBB/HSCI 426, MBB 726 Immune System I
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Unformatted text preview: Wednesday 5 October 2011 This lecture was taken from: Appendix, pp. 753 & 756-762 A recombined, functional, Ab or TcR transgene will dominate among lymphoctes in a transgenic mouse. After 10 generations of backcrossing, mice are 99% genetically identical Homologous recombination is used for knock-outs, and is essentially the same for knock-ins. Lox-Cre system for inactivating genes in specific tissues...
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This note was uploaded on 11/05/2011 for the course MBB 426 taught by Professor Scott during the Spring '11 term at Simon Fraser.

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Ch05.2-05Oct - Wednesday 5 October 2011 This lecture was...

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