Ch07.1-17Oct

Ch07.1-17Oct - GADS/LAT Guanine-nucleotide exchange factor...

Info iconThis preview shows pages 1–35. Sign up to view the full content.

View Full Document Right Arrow Icon
Ch. 6: Signaling through Immune System Receptors MBB/HSCI 426, MBB726 Immune System I Chapter 7: pp. 239-271
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Principles of Signaling Monday 17 Oct. 2011 First hour of lecture taken from: Ch. 7: pp. 239-247
Background image of page 2
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
T-cell Signaling This part of Monday’s lecture is taken from: Ch 7: pp. 247-258 and 2-242 (sections 7-15 and 18)
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 12
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 14
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Figure 8-30
Background image of page 16
Figure 8-29
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 18
Background image of page 19

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 20
Background image of page 21

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 22
Background image of page 23

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
CD28 Costimulation
Background image of page 24
Background image of page 25

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 26
Background image of page 27

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 28
Background image of page 29

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 30
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: GADS/LAT Guanine-nucleotide exchange factor Ras GRP Small G protein Ras 3 MAP kinases Raf, Mek, Erk (transciptional factor Elk1) First 1/2 transcription factor Fos (JNK kinase -> Jun) Antigen Co-receptor (initiates signal 2) [CD19 complex] CD28 Guanine-nucleotide exchange factor Grb2 adaptor, SOS (a GEF) Small G protein Ras 3 MAP kinases See above Second 1/2 transcription factor See above Transcription factor made by two 1/2s AP-1 Adaptor protein for Tec kinase BLNK LAT and SLP-76 Tec kinase (pleckstrin homology domain + SH2 & SH3) Btk Itk Phospholipase C-gamma Transcription factor activated by calcineurin NFAT Protein kinase C PKC- Transcription factor activated by Protein kinase C NF B...
View Full Document

Page1 / 35

Ch07.1-17Oct - GADS/LAT Guanine-nucleotide exchange factor...

This preview shows document pages 1 - 35. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online