Ch08.1-24%2628Oct

Ch08.1-24%2628Oct - Ch. 8: The Development and Survival of...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
Ch. 8: The Development and Survival of Lymphocytes: B cells MBB/HSCI 426, MBB726 Immune System I Chapter 8, 1 st Monday’s Lecture: pp. 275-290 Friday’s Lecture: pp. 316-324 & 327
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This Wednesday’s Lectures Ralph Pantophlet (FHS): HSCI 442: Immunology Lab, HSCI 477 Seminar in Vaccine Immunology & research opportunities in his lab Naveed Gulzar (MBB): Research in Scott lab On Nov 2 nd : Jonathan Choy (MBB): MBB/HSCI 427, MBB 727, Immune System II & research opportunities in his lab
Background image of page 2
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Positive selection : lymphocytes whose receptors interact weakly with self antigens, or bind antigen in a particular way, receive a survival signal Negative selection : lymphocytes with strongly self-reactive receptors are eliminated by apoptosis or anergy
Background image of page 4
HSC: self-renewing stem cell MPP: not self-renewing, gives rise to myeloid and lymphoid cells CLP: not self-renewing, gives rise to NK, B and T (?) cells Committed precursors
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Figure 7-5
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/05/2011 for the course MBB 426 taught by Professor Scott during the Spring '11 term at Simon Fraser.

Page1 / 43

Ch08.1-24%2628Oct - Ch. 8: The Development and Survival of...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online