Circulatory System - Blood

Circulatory System - Blood - The Circulatory System: BLood...

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The Circulatory System: BLood Assigned reading: pages 684-714 in Saladin 5th
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FUNCTIONS OF CIRCULATORY SYSTEM Transport O2, CO2, nutrients, wastes, hormones, and stem cells Protection inflammation, limit spread of infection, destroy microorganisms and cancer cells, neutralize toxins, and initiates clotting Regulation fluid balance, stabilizes pH of ECF, and temperature control
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Components and General Properties of Blood Liquid connective tissue – consisting of cells and extracellular matrix Plasma serum + fibers Formed elements erythrocytes (RBCs) platelets cell fragments leukocytes (WBCs) granulocytes neutrophils eosinophils basophils agranulocytes lymphocytes monocytes
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Separating Plasma From Formed Elements of Blood hematocrit - centrifuge blood to separate components erythrocytes settle first white blood cells and platelets 1% total volume buffy coat plasma complex mixture of water, proteins, nutrients, electrolytes, nitrogenous wastes, hormones, and gases Centrifuge Withdraw blood Plasma (55% of whole blood) Buffy coat: leukocytes and platelets (<1% of whole blood) Erythrocytes (45% of whole blood) Formed elements
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Plasma and Plasma Proteins 3 major categories of plasma proteins 1. fibrinogen precursor of fibrin threads that help form blood clots formed by liver 2. albumins – smallest and most abundant contributes to viscosity and osmolarity, influences blood pressure, flow and fluid balance formed by liver 3. globulins (antibodies) provide immune system functions formed by lymphocytes
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Properties of Blood Viscosity - resistance of a fluid to flow, resulting from cohesion of its particles whole blood 4.5 - 5.5 times as viscous as water Osmolarity of blood - the total molarity of those dissolved particles that cannot pass through the blood vessel wall if too high, blood absorbs too much water from other ECF if too low, too much water stays in tissues: edema optimum osmolarity is achieved by regulation of ions & proteins
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STARVATION AND PLASMA PROTEINS Hypoproteinemia deficiency of plasma proteins liver or kidney disease severe burns extreme starvation Kwashiorkor children with severe protein deficiency swollen abdomen from fluid accumulation in abdominal cavity
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HOW BLOOD IS PRODUCED Adult production of 400 billion platelets, 200 billion RBCs and
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This note was uploaded on 11/04/2011 for the course BIOL 252 taught by Professor Johnson during the Fall '07 term at UNC.

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Circulatory System - Blood - The Circulatory System: BLood...

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