Introduction to DNA

Introduction to DNA - Introduction to DNA Thursday,...

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Thursday, February 19, 2009 9:29 AM 1. Have been talking about transcription genetics 2. Molecular Genetics o Finding the Code Early 1900s people studying cells developed dyes that allowed them to see chromosomes. Meiosis (chromosome movement) made it obvious that was where info was Chromosome Contain Protein More complex Amino Acids Thought was that genetic info was in proteins because of complexity Deoxyribonucleic Acid (DNA) Griffith Pneuomonia experiments 1928 Pathogenic (deadly) bacteria Non pathogenic bacteria TRANSFORMATION Took pathogenic bacteria, injected into mice, mice died. Non pathogenic didn’t die. Tried to heat kill bacteria, then injected and mice lived. Mixed heat killed bacteria and non pathogenic bacteria and mice died. Found living pathogenic bacteria in mice. Had been transformed. Living non-pathogenic transformed into pathogenic bacteria. Avery, McCarty, and MacLeod 1944 Only pathogenic DNA needed for transformation Hershey and Chase Baceriophage Virus that attacks bacteria Bacteria phage Virus attacks cell, something goes in cell, and new viruses made. Bacteriophage Labeled DNA with P 32 (found inside) Labeled protein with S 35 (found outside) Found DNA went in and protein went outside Confirmed DNA is genetic material
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This note was uploaded on 11/05/2011 for the course BIOL 101 taught by Professor Hogan during the Fall '08 term at UNC.

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Introduction to DNA - Introduction to DNA Thursday,...

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