Hom04 - Molecular Genetics BSCI410 Homework 4; Lectures...

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Unformatted text preview: Molecular Genetics BSCI410 Homework 4; Lectures 13-18 Homework due at the beginning of class on Thursday, Nov. 11, 2010. The exam will be Nov. 18. Homework and review questions will be discussed at the review on Nov. 16.------------------------------------------------------------------------------------------------------------- ------------- 1 Homework questions . Please provide your answers on a separate sheet. Examine the following pedigree. A 1,2 B 1,2 A 1,3 B 1,3 A 1,2 B 1,2 A 1,2 B 1,3 1. (1 point) The A 1 alleles in the two brothers are identical by state (this just means that they are both A 1 ). Can you infer that they are also identical by descent? a) You don't know whether or not A 1 is identical by descent. b) You can conclude that A 1 is identical by descent. c) You can conclude A 1 is not identical by descent. 2. (1 point) The B 1 alleles in the two brothers are identical by state (this just means that they are both B 1 ). Can you infer that they are also identical by descent? a) You don't know whether or not B 1 is identical by descent. b) You can conclude that B 1 is identical by descent. c) You can conclude B 1 is not identical by descent. (Questions 3-5) Consider two populations, 1 and 2, that differ at two unlinked loci, A and B. In each population a specific allele is fixed at each locus ( i.e. all individuals in population 1 are homozygous for A 1 and B 1-- they have the genotype A 1,1 B 1,1 -- while all individuals in population 2 have the genotype A 2,2 B 2,2 ). You allow a large and equivalent number of individuals from the two populations -- for example, 500 males and 500 females from population 1 and 500 males and 500 females from population 2 -- to mate at random (and they do mate at random). 3. (1 point) Is locus A at Hardy-Weinberg equilibrium in the "G1" generation? 4. (1 point) What is the expected frequency of each of the four possible gametes transmitted from the G1 to the G2. The possible genotypes are A 1 B 1 , A 1 B 2 , A 2 B 1 and A 2 B 2 Molecular Genetics BSCI410 Homework 4; Lectures 13-18 Homework due at the beginning of class on Thursday, Nov. 11, 2010. The exam will be Nov. 18. Homework and review questions will be discussed at the review on Nov. 16.------------------------------------------------------------------------------------------------------------- ------------- 2 5. (1 point) Do the two alleles A 1 and B 1 show genetic association (linkage disequilibrium) in this G1 generation?...
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This note was uploaded on 11/07/2011 for the course BIO 325 taught by Professor Saxena during the Summer '08 term at University of Texas at Austin.

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Hom04 - Molecular Genetics BSCI410 Homework 4; Lectures...

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